What, you thought I was referring to something else? OK, so I’m a bit insensitive. But I get a lot of slack these days. As of earlier this morning, at approximately 2:47am, I dropped my last Tarceva pill. I had flirted with the idea of playing off a memorial theme for Tarceva’s last day. But that really would not have been appropriate. And in actuality, Tarceva has been an extremely good friend for over a year; but sometimes you just gotta let go. So this is more like a farewell party to a bud who is leaving town for far away places, never to be seen again. But he (sorry, I know it’s not PC but I just don’t see Tarceva in a feminine role) is not going to leave me high and dry. His cousin, with the cutesy name of AZD9291, will be getting the tag-off from Mr T. before he leaves town.
So why is the plug getting pulled on my 150mg, $200 per pill buddy? Weeeelll, in order to begin the new trial at UCSD, I have to be “purged” off Tarceva for 8 days. Even though the lab may not have the final results until the end of the week, the lung-onc specialist at UCSD does not want to waste another week on what should be a foregone conclusion. “Should be” being the operative phrase. Assuming the labs has enough tissue and assuming they confirm the T790M mutation by Friday, I should be popping my new buddy come next Wednesday the 16th. Let’s hope “assume” does not make an ass out of you and me. Or really, just me since you had nothing to do with it. Feels a little like diving off the high dive hoping there will be water in the pool by the time I reach it.
After I’ve waited all of this time, UCSD is now “fast-tracking” me so I can get off the dime. Get the show on the road. Put the pedal to the metal. What this means is that sometime in the next week I will be going through a battery of tests, one day of which will require a 10-hour stint spent doing multiple tests, waiting several hours, and testing again. And like it says on the shampoo bottle, lather-rinse-repeat again. I will also be getting a series of CT (kitty-kat) scans this week so they have a baseline to compare to down the road when the AZD9291 starts working its magic. Notice I said when.
Topic switch: look what I got in the mail today. As much as I would like to do my civic duty, I don‘t think that I have the time, or the inclination, right now for listening to someone sue someone for cutting an overhanging branch on their property. Anyone think of a good excuse I can use for getting out of it? Oh yeah, I have one. Duh.
I know I will get very little sympathy here but lately I find that I have to actually force myself to eat. I know I need to keep up my strength, but I have zero appetite and in many cases I actually have to make myself chow down something that I would ordinarily be powering down multiple helpings of. I mean, free pizza was dangled in front of me this afternoon and I had zero slices. Repeat: zero. A very weird feeling. Lost 10 pounds overall and don’t want to lose many more. Except soon I may be fitting into my 34’s that I haven’t worn in 6 years.
Audience participation time. Since AZD9291 is in clinical trial and not on the market, it does not have a trade, or cute, name. I don’t want to keep referring to it by that number so how about something like “Azzy” or “Azid?” Anyone have any other suggestions? Hey, when I write that book you all keep telling me I should write, you’ll be famous.
I imagine I’ll be blogging again within the week with more specific updates. Stay tuned.
Business as usual. Day at a time.